To adjust voltage, press the plus or minus buttons. The wattage range is 1-250 watts. To use the temperature setting, from the lock screen, hold both the plus and minus buttons together until the temperature screen is displayed. Pressing the minus button scrolls through Fahrenheit and Celsius. The Fahrenheit range is 200 - 600℉ and the Celsius range is 100 - 300℃ although the manual states that it stops at 230℃. Pressing the plus button will scroll to the OFF setting.
The DNA 250 also features stealth, power locked and resistance lock modes as well as eight customizable preset profile settings. I really enjoyed vaping with the Tuglyfe DNA 250. It's on the larger side, but I find it comfortable to use and lighter than expected. I also like the rounded edges and the high quality finish.